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L’expression de la surface Fel d 1 sur des eBioparticules d’origine végétale combine une activation immunitaire puissante et une hypoallergénicité

By octobre 9, 2022mars 10th, 2023No Comments

disponible en anglais seulement

Allergen immunotherapy (AIT) still remains the only disease- modifying treatment for immunoglobulin E (IgE)-mediated allergies with proven sustained efficacy upon discontinuation of the treatment, provided it is administered regularly for at least 3 years. Aluminum salts still remain a common depot and adjuvant for subcutaneous AIT that moderately reduce allergenicity; however, the risk of severe allergic reactions persists, making careful updosing protocols necessary. These characteristics justify the need for shorter treatments with improved safety profiles.

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